Defining lipid mediators of insulin resistance: controversies and challenges
نویسندگان
چکیده
منابع مشابه
Lipid mediators of insulin resistance.
Lipid abnormalities such as obesity, increased circulating free fatty acid levels, and excess intramyocellular lipid accumulation are frequently associated with insulin resistance. These observations have prompted investigators to speculate that the accumulation of lipids in tissues not suited for fat storage (e.g., skeletal muscle and liver) is an underlying component of insulin resistance and...
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Imbalance between nutritional intake and energy expenditure has been described to culminate in obesity, which predisposes to insulin resistance and type 2 diabetes mellitus. In such states of energy oversupply, excess amounts of lipids are available in tissues and circulation. Over the past years, an increasingly important role in development of skeletal muscle (SkM) insulin resistance has been...
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N Ferreira BSc, MBChB, HDip Orth(SA), FC Orth(SA), MMed(Orth) Tumour, Sepsis and Reconstruction Unit, Department of Orthopaedics, Grey’s Hospital, University of KwaZulu-Natal LC Marais MBChB, FCS Orth(SA), MMed(Ortho) Tumour, Sepsis and Reconstruction Unit, Department of Orthopaedics, Grey’s Hospital, University of KwaZulu-Natal C Aldous BSc, BSc(Hons), MSc, PhD Medical Research Scientist, Scho...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2019
ISSN: 0952-5041,1479-6813
DOI: 10.1530/jme-18-0023